A novel rigid annuloplasty ring for aortic valve reconstruction: An in vitro investigation

Doreen Richardt*, Bence Bucsky, Efstratios I. Charitos, Hans Hinrich Sievers, Michael Scharfschwerdt

*Korrespondierende/r Autor/-in für diese Arbeit
6 Zitate (Scopus)


Background Remodeling of the dilated valve annulus with a prosthetic ring for repair of valve insufficiency is a well-established concept in mitral and tricuspid valve surgery and may also be suitable for aortic valve reconstruction. A novel rigid aortic annuloplasty ring was tested in vitro. Methods Ten fresh porcine aortic roots were investigated in a pulsatile flow simulator before surgery (group N), after patch dilatation of the annulus (group D), and after reconstruction using a rigid annuloplasty ring (group R). The ring was designed to (1) prevent contact with the leaflets, reducing the risk of contact injury, (2) be applicable to all valve phenotypes, (3) prevent injury to the conduction bundle, and (4) be implantable from inside the aortic root (subvalvular). For each group pressure gradient, leakage volume, and coaptation height were measured. Results With the annuloplasty ring, regurgitation volume decreased from -8.50 ± 1.91 mL (group D) to -4.75 ± 1.66 mL (group R; p < 0.0003), not different from group N. Coaptation height of the leaflets increased from 0.62 ± 0.08 mm (group D) to 0.77 ± 0.11 mm (group R; p < 0.005), similar to group N. Mean pressure gradient increased from 2.98 ± 0.38 mm Hg (group D) to 3.72 ± 0.40 mm Hg (group R; p < 0.0001). Conclusions This novel aortic annuloplasty ring has the potential for supporting aortic valve reconstruction by remodeling the subvalvular area.

ZeitschriftAnnals of Thoracic Surgery
Seiten (von - bis)811-815
PublikationsstatusVeröffentlicht - 01.03.2014


Untersuchen Sie die Forschungsthemen von „A novel rigid annuloplasty ring for aortic valve reconstruction: An in vitro investigation“. Zusammen bilden sie einen einzigartigen Fingerprint.