A new survival score for patients scheduled for palliative irradiation of locally advanced carcinoma of the head-and-neck

Dirk Rades*, Christian Staackmann, Julika Ribbat-Idel, Sven Perner, Christian Idel, Karl L. Bruchhage, Samer G. Hakim, Steven E. Schild

*Korrespondierende/r Autor/-in für diese Arbeit

Abstract

Background/Aim: Patients with advanced squamous cell carcinoma of the head-and-neck (SCCHN) may be assigned to palliative irradiation. A survival score was developed for this group to support treatment personalization. Patients and Methods: Seventy-eight patients who received palliative irradiation for SCCHN and had complete data regarding performance score, pre-radiotherapy hemoglobin levels, and main tumor site were included in this retrospective study. Six-month survival rates of these factors were divided by 10 (factor scores) and added for each patient (total patient scores). Results: Total patient scores ranged between 8 and 15 points. Three groups were designed based on the 6-month survival rates, namely 8-9 (n=15), 11-13 (n=36), and 14-15 (n=27) points. Six-month survival rates were 13%, 28%, and 63%, and median survival times were 1, 2, and 11 months (p=0.001). Conclusion: A new survival score including three prognostic groups was developed. This new tool can help physicians when designing personalized treatments for patients with SCCHN scheduled for palliative irradiation.

OriginalspracheEnglisch
ZeitschriftAnticancer Research
Jahrgang41
Ausgabenummer6
Seiten (von - bis)3055-3058
Seitenumfang4
ISSN0250-7005
DOIs
PublikationsstatusVeröffentlicht - 06.2021

Strategische Forschungsbereiche und Zentren

  • Profilbereich: Lübeck Integrated Oncology Network (LION)
  • Zentren: Universitäres Cancer Center Schleswig-Holstein (UCCSH)

Fingerprint

Untersuchen Sie die Forschungsthemen von „A new survival score for patients scheduled for palliative irradiation of locally advanced carcinoma of the head-and-neck“. Zusammen bilden sie einen einzigartigen Fingerprint.

Zitieren