828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser

Marie Klufts; Alejandro Martínez Jiménez; Simon Lotz; Muhammad Asim Bashir; Tom Pfeiffer; Alexander Mlynek; Wolfgang Wieser; Alexander Chamorovskiy; Adrian Bradu; Adrian Podoleanu; Robert Huber

doi:10.1364/BOE.504302

828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser

Marie Klufts, Alejandro Martínez Jiménez, Simon Lotz, Muhammad Asim Bashir, Tom Pfeiffer, Alexander Mlynek, Wolfgang Wieser, Alexander Chamorovskiy, Adrian Bradu, Adrian Podoleanu, Robert Huber

Institut für Biomedizinische Optik

Abstract

This paper presents a Fourier domain mode locked (FDML) laser centered around 840x2005;nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of 40x2005;nm. An axial resolution of x223C;9.9 x00B5;m in water and a 1.4x2005;cm sensitivity roll-off are achieved. Utilizing a complex master-slave (CMS) recalibration method and due to a sufficiently high sensitivity of 84.6x2005;dB, retinal layers of the human eye in-vivo can be resolved during optical coherence tomography (OCT) examination. The developed FDML laser enables acquisition rates of 3D-volumes with a size of 200x2009;x00D7;x2009;100x2009;x00D7;x2009;256 voxels in under 100 milliseconds. Detailed information on the FDML implementation, its challenging design tasks, and OCT images obtained with the laser are presented in this paper.

Originalsprache	Englisch
Zeitschrift	Biomed. Opt. Express
Jahrgang	14
Ausgabenummer	12
Seiten (von - bis)	6493-6508
Seitenumfang	16
DOIs	https://doi.org/10.1364/BOE.504302
Publikationsstatus	Veröffentlicht - 01.12.2023

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https://opg.optica.org/boe/abstract.cfm?URI=boe-14-12-6493

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title = "828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser",

abstract = "This paper presents a Fourier domain mode locked (FDML) laser centered around840 nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of40 nm. An axial resolution of ∼9.9 µm in water and a 1.4 cm sensitivity roll-off are achieved.Utilizing a complex master-slave (CMS) recalibration method and due to a sufficiently highsensitivity of 84.6 dB, retinal layers of the human eye in-vivo can be resolved during opticalcoherence tomography (OCT) examination. The developed FDML laser enables acquisitionrates of 3D-volumes with a size of 200 × 100 × 256 voxels in under 100 milliseconds. Detailedinformation on the FDML implementation, its challenging design tasks, and OCT images obtainedwith the laser are presented in this paper.",

author = "Marie Klufts and Jim{\'e}nez, {Alejandro Mart{\'i}nez} and Simon Lotz and Bashir, {Muhammad Asim} and Tom Pfeiffer and Alexander Mlynek and Wolfgang Wieser and Alexander Chamorovskiy and Adrian Bradu and Adrian Podoleanu and Robert Huber",

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doi = "10.1364/BOE.504302",

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T1 - 828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser

AU - Klufts, Marie

AU - Jiménez, Alejandro Martínez

AU - Lotz, Simon

AU - Bashir, Muhammad Asim

AU - Pfeiffer, Tom

AU - Mlynek, Alexander

AU - Wieser, Wolfgang

AU - Chamorovskiy, Alexander

AU - Bradu, Adrian

AU - Podoleanu, Adrian

AU - Huber, Robert

PY - 2023/12/1

Y1 - 2023/12/1

N2 - This paper presents a Fourier domain mode locked (FDML) laser centered around840 nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of40 nm. An axial resolution of ∼9.9 µm in water and a 1.4 cm sensitivity roll-off are achieved.Utilizing a complex master-slave (CMS) recalibration method and due to a sufficiently highsensitivity of 84.6 dB, retinal layers of the human eye in-vivo can be resolved during opticalcoherence tomography (OCT) examination. The developed FDML laser enables acquisitionrates of 3D-volumes with a size of 200 × 100 × 256 voxels in under 100 milliseconds. Detailedinformation on the FDML implementation, its challenging design tasks, and OCT images obtainedwith the laser are presented in this paper.

AB - This paper presents a Fourier domain mode locked (FDML) laser centered around840 nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of40 nm. An axial resolution of ∼9.9 µm in water and a 1.4 cm sensitivity roll-off are achieved.Utilizing a complex master-slave (CMS) recalibration method and due to a sufficiently highsensitivity of 84.6 dB, retinal layers of the human eye in-vivo can be resolved during opticalcoherence tomography (OCT) examination. The developed FDML laser enables acquisitionrates of 3D-volumes with a size of 200 × 100 × 256 voxels in under 100 milliseconds. Detailedinformation on the FDML implementation, its challenging design tasks, and OCT images obtainedwith the laser are presented in this paper.

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DO - 10.1364/BOE.504302

M3 - Journal articles

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EP - 6508

JO - Biomed. Opt. Express

JF - Biomed. Opt. Express

IS - 12

ER -

828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser

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