Braun Rüdiger

Publikationen

Publikationen pro Jahr 2018 2021 2022 2023 2024

• 22 Zeitschriftenaufsätze
• 1 Leitartikel

Publikationen pro Jahr

Publikationen pro Jahr

Suchergebnisse

• 2024

  RAC1b Collaborates with TAp73α-SMAD4 Signaling to Induce Biglycan Expression and Inhibit Basal and TGF-β-Driven Cell Motility in Human Pancreatic Cancer

  Ungefroren, H., Reimann, J., Konukiewitz, B., Braun, R., Wellner, U. F., Lehnert, H. & Marquardt, J. U., 01.2024, in: Biomedicines. 12, 1, 199.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Biglycan 100%
  • Transforming Growth Factors 70%
  • Pancreatic Neoplasms 63%
  • Cell Movement 54%
  • Adenocarcinoma 26%
• 2023

  Elucidation of the Role of SMAD4 in Epithelial–Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of DPC4 Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

  Ungefroren, H., Konukiewitz, B., Braun, R., Wellner, U. F., Keck, T. & Marquardt, J. U., 18.01.2023, in: Cancers. 15, 3, 581.

  Publikation: Beiträge in Fachzeitschriften › Leitartikel

  • Adenocarcinoma 100%
  • Survival Rate 48%
  • Neoplasms 41%
  • Mortality 32%

• Establishment and Molecular Characterization of Two Patient-Derived Pancreatic Ductal Adenocarcinoma Cell Lines as Preclinical Models for Treatment Response

  Braun, R., Lapshyna, O., Watzelt, J., Drenckhan, M., Künstner, A., Färber, B., Hael, A. A. M., Bolm, L., Honselmann, K. C., Konukiewitz, B., Castven, D., Spielmann, M., Gorantla, S. P., Busch, H., Marquardt, J. U., Keck, T., Wellner, U. F. & Ungefroren, H., 11.02.2023, in: Cells. 12, 4, 587.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Adenocarcinoma 100%
  • Cell Line 75%
  • Transforming Growth Factors 57%
  • gemcitabine 40%
  • Cadherins 36%

• Molecular profiling and specific targeting of gemcitabine-resistant subclones in heterogeneous pancreatic cancer cell populations

  Färber, B., Lapshyna, O., Künstner, A., Kohl, M., Sauer, T., Bichmann, K., Heckelmann, B., Watzelt, J., Honselmann, K., Bolm, L., ten Winkel, M., Busch, H., Ungefroren, H., Keck, T., Gemoll, T., Wellner, U. F. & Braun, R., 2023, in: Frontiers in Oncology. 13, 1230382.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • gemcitabine 100%
  • Pancreatic Neoplasms 84%
  • Cell Line 53%
  • Population 35%
  • Adenocarcinoma 14%

• Prognostic factors after resection of locally advanced non-functional pancreatic neuroendocrine neoplasm: an analysis from the German Cancer Registry Group of the Society of German Tumor Centers

  Abdalla, T. S. A., Klinkhammer-Schalke, M., Zeissig, S. R., Tol, K. K. V., Honselmann, K. C., Braun, R., Bolm, L., Lapshyn, H., Litkevych, S., Zemskov, S., Begum, N., Kulemann, B., Hummel, R., Wellner, U. F., Keck, T. & Deichmann, S., 09.2023, in: Journal of Cancer Research and Clinical Oncology. 149, 11, S. 8535-8543 9 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Pancreatic Neoplasms 100%
  • Registries 83%
  • Margins of Excision 83%
  • Survival 58%
  • Lymph Nodes 37%
  1 Zitat (Scopus)

• TAp73 Inhibits EMT and Cell Migration in Pancreatic Cancer Cells through Promoting SMAD4 Expression and SMAD4-Dependent Inhibition of ERK Activation

  Ungefroren, H., Konukiewitz, B., Braun, R., Wellner, U. F., Lehnert, H. & Marquardt, J. U., 08.2023, in: Cancers. 15, 15, 3791.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Extracellular Signal-Regulated MAP Kinases 100%
  • Transforming Growth Factors 96%
  • Pancreatic Neoplasms 87%
  • Cell Movement 75%
  • Psychological Inhibition 75%
• 2022

  Clinical Outcome and Prognostic Factors of Pancreatic Adenosquamous Carcinoma Compared to Ductal Adenocarcinoma—Results from the German Cancer Registry Group

  Braun, R., Klinkhammer-Schalke, M., Zeissig, S. R., Kleihus van Tol, K., Bolm, L., Honselmann, K. C., Petrova, E., Lapshyn, H., Deichmann, S., Abdalla, T. S. A., Heckelmann, B., Bronsert, P., Zemskov, S., Hummel, R., Keck, T. & Wellner, U. F., 08.2022, in: Cancers. 14, 16, 3946.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Adenosquamous Carcinoma 100%
  • Pancreatic Carcinoma 85%
  • Registries 56%
  • Pancreas 43%
  • Adenocarcinoma 26%
  3 Zitate (Scopus)

• Overexpression of integrin alpha 2 (ITGA2) correlates with poor survival in patients with pancreatic ductal adenocarcinoma

  Deichmann, S., Schindel, L., Braun, R., Bolm, L., Taylor, M., Deshpande, V., Schilling, O., Bronsert, P., Keck, T., Ferrone, C., Wellner, U. & Honselmann, K., 2022, in: Journal of Clinical Pathology.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Integrin alpha Chains 100%
  • Plakophilins 87%
  • Adenylate Kinase 70%
  • Adenocarcinoma 54%
  • Survival 38%

• Suppressive Role of ACVR1/ALK2 in Basal and TGFβ1-Induced Cell Migration in Pancreatic Ductal Adenocarcinoma Cells and Identification of a Self-Perpetuating Autoregulatory Loop Involving the Small GTPase RAC1b

  Ungefroren, H., Braun, R., Lapshyna, O., Konukiewitz, B., Wellner, U. F., Lehnert, H. & Marquardt, J. U., 10.2022, in: Biomedicines. 10, 10, 2640.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Monomeric GTP-Binding Proteins 100%
  • Transforming Growth Factors 89%
  • Cell Movement 69%
  • Adenocarcinoma 66%
  • RNA Interference 54%
  1 Zitat (Scopus)

• The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC‐1—A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting

  Ungefroren, H., Thürling, I., Färber, B., Kowalke, T., Fischer, T., De Assis, L. V. M., Braun, R., Castven, D., Oster, H., Konukiewitz, B., Wellner, U. F., Lehnert, H. & Marquardt, J. U., 01.05.2022, in: Cancers. 14, 9, 2057.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Epithelial Cells 100%
  • Cell Line 82%
  • Cell Plasticity 62%
  • Phenotype 56%
  • Transforming Growth Factors 48%
  4 Zitate (Scopus)
• 2021

  A comparative endocrine trans-differentiation approach to pancreatic ductal adenocarcinoma cells with different EMT phenotypes identifies quasi-mesenchymal tumor cells as those with highest plasticity

  Schmidtlein, P. M., Volz, C., Braun, R., Thürling, I., Lapshyna, O., Wellner, U. F., Konukiewitz, B., Lehnert, H., Marquardt, J. U. & Ungefroren, H., 09.2021, in: Cancers. 13, 18, 4663.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Epithelial-Mesenchymal Transition 100%
  • Adenocarcinoma 75%
  • Phenotype 57%
  • Endocrine Cells 38%
  • Islets of Langerhans 32%
  1 Zitat (Scopus)

• Activation of a ductal-to-endocrine transdifferentiation transcriptional program in the pancreatic cancer cell line PANC-1 is controlled by Rac1 and RAC1b through antagonistic regulation of stemness factors

  Schmidtlein, P. M., Volz, C., Hackel, A., Thürling, I., Castven, D., Braun, R., Wellner, U. F., Konukiewitz, B., Riemekasten, G., Lehnert, H., Marquardt, J. U. & Ungefroren, H., 01.11.2021, in: Cancers. 13, 21, 5541.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Pancreatic Neoplasms 100%
  • Cell Line 62%
  • Ectopic Gene Expression 33%
  • Neoplastic Stem Cells 32%
  • Protein Isoforms 24%

• A simple nomogram for early postoperative risk prediction of clinically relevant pancreatic fistula after pancreatoduodenectomy

  Honselmann, K. C., Antoine, C., Frohneberg, L., Deichmann, S., Bolm, L., Braun, R., Lapshyn, H., Petrova, E., Keck, T., Wellner, U. & Bausch, D., 11.2021, in: Langenbeck's Archives of Surgery. 406, 7, S. 2343-2355 13 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Pancreatic Fistula 100%
  • Nomograms 92%
  • Pancreaticoduodenectomy 89%
  • Lipase 20%
  • Linear Models 14%

• A simple preoperative stratification tool predicting the risk of postoperative pancreatic fistula after pancreatoduodenectomy

  Lapshyn, H., Petruch, N., Thomaschewski, M., Sondermann, S., May, K., Frohneberg, L., Petrova, E., Zemskov, S., Honselmann, K. C., Braun, R., Keck, T., Wellner, U. F. & Bolm, L., 08.2021, in: Pancreatology. 21, 5, S. 957-964 8 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Pancreatic Fistula 100%
  • Pancreaticoduodenectomy 89%
  • Nomograms 25%
  • Area Under Curve 11%
  • Logistic Models 8%

• Organotypic Slice Cultures as Preclinical Models of Tumor Microenvironment in Primary Pancreatic Cancer and Metastasis

  Braun, R., Lapshyna, O., Eckelmann, S., Honselmann, K., Bolm, L., Ten Winkel, M., Deichmann, S., Schilling, O., Kruse, C., Keck, T., Wellner, U., Bronsert, P. & Brandenburger, M., 22.06.2021, in: Journal of Visualized Experiments. 172

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Tumor Microenvironment 100%
  • Pancreatic Neoplasms 91%
  • Neoplasm Metastasis 59%
  • Sepharose 16%
  • Proteome 16%

• Postoperative Outcomes of Tangential versus Segmental Resection and End-to-end Reconstruction of the Superior Mesenterico-Portal Vein During Pancreatoduodenectomy for Pancreatic Adenocarcinoma: A Single-Center Experience

  Lapshyn, H., Schulte, T., Petruch, N., Petrova, E., Honselmann, K., Deichmann, S., Braun, R., Kulemann, B., Hoeppner, J., Rades, D., Keck, T., Wellner, U. F., Bausch, D. & Bolm, L., 2021, in: Anticancer Research. 41, 10, S. 5123-5130 8 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Pancreaticoduodenectomy 100%
  • Portal Vein 86%
  • Adenocarcinoma 66%
  • Morbidity 33%
  • Margins of Excision 29%

• Radiological prediction of portal vein infiltration in patients with pancreatic ductal adenocarcinoma

  Lapshyn, H., Schulte, T., Sondermann, S., May, K., Petrova, E., Honselmann, K. C., Braun, R., Zemskov, S., Keck, T., Wellner, U. F., Bausch, D. & Bolm, L., 01.01.2021, in: Pancreatology. 21, 1, S. 155-162 8 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Portal Vein 100%
  • Adenocarcinoma 76%
  • Pancreaticoduodenectomy 21%
  • Superior Mesenteric Artery 10%
  • Neoadjuvant Therapy 10%

• Survival Outcome and Prognostic Factors for Pancreatic Acinar Cell Carcinoma: Retrospective Analysis from the German Cancer Registry Group

  Petrova, E., Wellner, J., Nording, A. K., Braun, R., Honselmann, K. C., Bolm, L., Hummel, R., Klinkhammer-Schalke, M., Zeissig, S. R., Kleihues van Tol, K., Timme-Bronsert, S., Bronsert, P., Zemskov, S., Keck, T. & Wellner, U. F., 2021, in: Cancers. 13, 23

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Acinar Cell Carcinoma 100%
  • Pancreatic Carcinoma 82%
  • Registries 54%
  • Survival 37%
  • Adenocarcinoma 30%
• 2020

  Single-Cell-Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response

  Braun, R., Anthuber, L., Hirsch, D., Wangsa, D., Lack, J., McNeil, N. E., Heselmeyer-Haddad, K., Torres, I., Wangsa, D., Brown, M. A., Tubbs, A., Auslander, N., Gertz, E. M., Brauer, P. R., Cam, M. C., Sackett, D. L., Habermann, J. K., Nussenzweig, A., Ruppin, E., Zhang, Z., &2 mehrRosenberg, D. W. & Ried, T., 01.07.2020, in: Clinical cancer research : an official journal of the American Association for Cancer Research. 26, 13, S. 3468-3480 13 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Chemoradiotherapy 100%
  • Carcinoma 92%
  • Cell Line 83%
  • Rectal Neoplasms 71%
  • Clone Cells 37%
• 2019

  Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells

  Wangsa, D., Braun, R., Stuelten, C. H., Brown, M., Bauer, K. M., Emons, G., Weston, L. A., Hu, Y., Yang, H. H., Vila-Casadesús, M., Lee, M. P., Brauer, P., Warner, L., Upender, M., Hummon, A. B., Camps, J. & Ried, T., 01.07.2019, in: Neoplasia (United States). 21, 7, S. 721-729 9 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Aneuploidy 100%
  • Chromosomes, Human, Pair 13 98%
  • Transcriptome 85%
  • Clone Cells 44%
  • Colorectal Neoplasms 44%

• Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression

  Braun, R., Ronquist, S., Wangsa, D., Chen, H., Anthuber, L., Gemoll, T., Wangsa, D., Koparde, V., Hunn, C., Habermann, J. K., Heselmeyer-Haddad, K., Rajapakse, I. & Ried, T., 01.04.2019, in: Neoplasia (United States). 21, 4, S. 401-412 12 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Chromosomes, Human, Pair 7 100%
  • Aneuploidy 84%
  • Chromosomes 61%
  • Genome 53%
  • Gene Expression 46%
• 2018

  Gender-related differences in patients with colon cancer resection

  Braun, R., Benecke, C., Nolde, J., Kleemann, M., Zimmermann, M., Keck, T. & Laubert, T., 01.04.2018, in: European Surgery - Acta Chirurgica Austriaca. 50, 2, S. 50-57 8 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Colonic Neoplasms 100%
  • Laparoscopy 40%
  • Survival Rate 33%
  • Anastomotic Leak 26%
  • Colorectal Neoplasms 17%

• Radical Resection of Locally Recurrent Colorectal Cancer Significantly Improves Overall Survival: A Single-Center Cohort Study

  Braun, R., Bruch, H-P., Keck, T., Benecke, C. & Hoffmann, M., 01.07.2018, in: Digestive surgery. S. 1-9 9 S.

  Publikation: Beiträge in Fachzeitschriften › Zeitschriftenaufsätze › Forschung › Begutachtung

  • Colorectal Neoplasms 100%
  • Cohort Studies 85%
  • Survival 69%
  • Neoplasms 16%
  • Combined Modality Therapy 13%